The Z10 PE D16 WS motherboard is generally compatible with the older Intel Xeon E5 family CPUs, specifically the E5-2600 V1 and V2 series. However, compatibility can depend on the specific model of the Xeon E5 CPU you intend to use. Make sure to check the motherboard's documentation for the exact CPU support list and verify that your BIOS is updated to the latest version, as this can affect compatibility. Additionally, ensure your power supply and cooling solutions are sufficient for the Xeon E5 CPUs, as they can have different power requirements compared to consumer-grade processors.
