Willem_NLMy car works with the same cable (and a few others), whichever way I insert it, with the Pixel 5, Samsung S10e, Sony XZ1 Compact and Xiaomi Mi Max 3. But not with the Zenfone 8, which also has issues with other cables (same car) - and other cars. The conclusion is not really premature, but comes after lot of anecdotal data. I don't know what causes the USB-C issues on the Z8, but it stands alone, so to speak.
That conclusion is a bit premature. It looks like a timing problem on the USB bus. You will have to measure with special equipment who is causing the timing issue. It is a collaboration between two devices, it is impossible to say in advance who will go wrong with timing.
So it can be the Zenfone, but also the car. In addition to timing, impedance mismatch can also be the cause. Due to the high speeds, a USB connection is very prone to errors.
Fortunately, there is a work arround for this problem with the USB hub.