Some of Windows 10 users are reporting to have faced a peculiar problem when they try to run .exe files on their computer, then .exe files aren't running. If you're facing a similar kind of error on your computer, don’t worry. There are fixes available to resolve your problem. The cause behind the problem of .exe files, not running is often many, except for the majority of the users, it's a registry error. Let’s keep the reasons aside and go for the fixes. Methods to Open .EXE Files in Windows 10 There are multiple ways to resolve this error; here, we'll cover the most useful methods for fixing “EXE files not opening in Windows 10.” 1. By changing the registry values Due to unknown reasons, the values in your system registry often get changed that prevents .exe files from opening. you'll change the default registry settings, following the below steps: . Press Window + R on your system and type cmd to launch a command prompt. . On the command prompt, type Regedit and press enter. . Registry Editor will appear on the screen, within the left pane, click HKEY_CLASSES_ROOT.exe. . In the right pane, you will see the registry keys. Click the Default key and set the information value to exefile. . After changing the key value, click the HKEY_CLASSES_ROOTexefileshellopencommand key within the left pane. . just like above, click the Default key and change its value to “%1” %*. . Now, restart your computer, you can check if the problem is fixed. For some users, this method might add Safe mode. However, if it still doesn’t work for you, then check other methods mentioned below. 2. turn off Windows Firewall Every genuine Windows comes integrated with Firewall protection to protect the system from external malware attacks. Disabling Windows Firewall also can fix this issue, as reported by some users. To disable Windows Firewall, you’ll need to launch your computer in Safe Mode, then follow the below steps: . After starting the computer in Safe Mode, press Windows + S to enter Windows Firewall and select Windows Firewall from there. . Click Turn Windows Firewall On or Off. in the opened wizard, select turn off Windows Firewall for both Private network settings and Public network settings, and then click ok to save changes. . After turning off the Windows Firewall, check if the problem is still persisting or not.